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北京地區(qū)種植不同種源的柴胡藥材質(zhì)量分析

發(fā)布時(shí)間:2019-08-29 來(lái)源: 短文摘抄 點(diǎn)擊:


  摘要 目的:通過(guò)田間種植試驗(yàn),分析不同種源的柴胡藥材質(zhì)量,為確定適宜北京地區(qū)種植柴胡的種源提供技術(shù)依據(jù)。方法:在北京市順義區(qū)設(shè)置田間試驗(yàn),種植從河北安國(guó)藥材市場(chǎng)、安徽亳州藥材市場(chǎng)、中國(guó)醫(yī)學(xué)科學(xué)院藥用植物研究所購(gòu)買的3個(gè)種源的柴胡,采用紫外可見分光光度法及高效液相色譜(HPLC)法,測(cè)定藥材樣品中的柴胡總皂苷、柴胡皂苷a、柴胡皂苷c和柴胡皂苷d的含量,以甘肅、山西種植柴胡藥材為對(duì)照,評(píng)價(jià)北京地區(qū)3個(gè)不同種源的柴胡藥材質(zhì)量。結(jié)果:3種不同種源的柴胡藥材,在柴胡總皂苷、柴胡皂苷a、柴胡皂苷c、柴胡皂苷d含量等化學(xué)成分指標(biāo)與甘肅、山西種植柴胡藥材的差異無(wú)統(tǒng)計(jì)學(xué)意義,且符合中華人民共和國(guó)藥典的標(biāo)準(zhǔn),其中河北安國(guó)藥材市場(chǎng)、中國(guó)醫(yī)學(xué)科學(xué)院藥用植物研究所種源的藥材質(zhì)量更優(yōu)。結(jié)論:北京地區(qū)是種植柴胡的適宜產(chǎn)區(qū),種源可從河北安國(guó)藥材市場(chǎng)或中國(guó)醫(yī)學(xué)科學(xué)院藥用植物研究所購(gòu)買。
  關(guān)鍵詞 柴胡;種植;藥材質(zhì)量;北京地區(qū)
  Medicinal Materials Quality Analysis of Different Provenances of Radix Bupleuri Planted in Beijing
  Xue Wenfeng1,Liu Changli1,2,Chen Yan1
 。1 School of Traditional Chinese Medicine,Capital Medicine University, Beijing 100069,China; 2 Beijing Key Lab of TCM Collateral Disease Teory Reaserch, Beijing 100069, China)
  Abstract Objective:To analysis of different provenances of radix bupleuri medicinal materials quality using field planting test, and to determine the provenance of suitable cultivation of radix bupleuri in Beijing. Methods:Field experiment was set in Shunyi district of Beijing, growing 3 provenances of radix bupleuri bought from Hebei Anguo medicine market, Anhui Bozhou medicine market and Chinese academy of medical sciences institute of medicinal plant. By ultravioletvisible spectrophotometry and high performance liquid chromatography (HPLC) method, total saponins in radix bupleuri, radix bupleuri saponins (a,b and c) were measured. Compared with those cultivated in Gansu and Shanxi, those three different provenance of radix bupleuri medicinal materials′ quality were evaluated. Results:Three different provenance of radix bupleuri had few difference comparing with those cultivated in Gansu and Shanxi in total saponins in radix bupleuri,and radix bupleuri saponins (a,b and c), besides, it met with Chinese pharmacopoeia standards, in which product of Hebei Anguo medicine market and Chinese academy of medical sciences institute of medicinal plant shared better quality.Conclusion:Beijing is suitable for planting of radix bupleuri, and provenance from hebei anguo medicine market or the Chinese academy of medical sciences institute of medicinal plant can be purchased.
  Key Words Radix bupleuri; Planting; Medicinal materials′ quality; Beijing
  中圖分類號(hào):R282.2文獻(xiàn)標(biāo)識(shí)碼:Adoi:10.3969/j.issn.1673-7202.2017.03.043
  柴胡性辛、苦、微寒,入肝、膽、肺經(jīng),具有疏散退熱,疏肝解郁,舉陽(yáng)氣的功效,用于感冒發(fā)寒熱往來(lái)、胸脅脹痛、月經(jīng)不調(diào)、子宮脫垂脫等證[1]。始載于《神農(nóng)本草經(jīng)》,在我國(guó)已有兩千多年的使用歷史。2015版《中華人民共和國(guó)藥典》收錄其來(lái)源為傘形科植物柴胡Bupleurum chinese DC.或狹葉柴胡Bupleurum scorzonerifolium willd.的干燥根。
  柴胡藥材以野生品種應(yīng)用為主,隨著對(duì)柴胡藥材的使用量的增加,野生柴胡不足以提供市場(chǎng)的需求。我國(guó)北方一些省區(qū)已開始進(jìn)行柴胡的人工種植,而且柴胡的栽培技術(shù)發(fā)展迅速。但是由于柴胡的種植品種混亂[2],以及不同的種植品種、環(huán)境、地域、年限以及種植方法使得不同地區(qū)的柴胡質(zhì)量參差不齊[3]。歷史上北京沿燕山山脈一帶山區(qū)是北柴胡的主要產(chǎn)區(qū)之一。早在1992年在北京密云懷柔就有種植三島柴胡的文獻(xiàn)[4],后來(lái)李勇等[5]在延慶種植北柴胡,并且對(duì)種植北柴胡根腐病的病原菌鑒定,楊成民等[6]研究了平谷區(qū)種植北柴胡皂苷含量動(dòng)態(tài)變化,建議柴胡在10月底果實(shí)成熟期適于采收。順義區(qū)位于北京市東北部,地處燕山南麓,年平均氣溫為11.5 ℃,年均相對(duì)濕度50%,年均降雨量約625 mm。安徽亳州藥材市場(chǎng)、河北安國(guó)藥材市場(chǎng)等主要中藥藥材市場(chǎng),市場(chǎng)主流商品種植北柴胡產(chǎn)地以甘肅和山西產(chǎn)地為主。

相關(guān)熱詞搜索:北京地區(qū) 柴胡 同種 藥材 種植

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