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血漿白蛋白Alb及血紅蛋白Hb水平與重型顱腦損傷患者預(yù)后的相關(guān)性

發(fā)布時(shí)間:2018-06-24 來源: 短文摘抄 點(diǎn)擊:


  [摘要] 目的 探討重型顱腦損傷(STBI)患者血漿白蛋白(Alb)及血紅蛋白(Hb)水平與預(yù)后的相關(guān)性。方法 方便選取2016年5月—2017年4月該院ICU收治的64例STBI患者為研究對(duì)象,依治療方式不同將入選病例分為兩組。對(duì)照組32例,患者入院后立即給予及時(shí)正確地急救處理、依指征行腦外科手術(shù)及非手術(shù)治療;實(shí)驗(yàn)組32例,患者在對(duì)照組治療基礎(chǔ)上輸注人血白蛋白和懸浮紅細(xì)胞以維持正常Alb及Hb水平。記錄兩組STBI患者治療期間血漿Alb水平、Hb水平及格拉斯哥昏迷評(píng)分(GCS),對(duì)比觀察Alb及Hb水平與STBI患者預(yù)后的相關(guān)性。結(jié)果 實(shí)驗(yàn)組生存率90.6%,死亡率9.4%,Alb(34.6±2.8)g/L,Hb(99.3±6.4)g/L,各項(xiàng)指標(biāo)均優(yōu)于對(duì)照組(P<0.05),Alb<30 g/L、Hb<90 g/L是STBI患者死亡危險(xiǎn)因素。結(jié)論 血漿白蛋白及血紅蛋白水平與重型顱腦損傷患者預(yù)后存在密切關(guān)聯(lián),維持Alb≥30 g/L、Hb≥90 g/L對(duì)STBI患者預(yù)后具有重要意義。
  [關(guān)鍵詞] 重型顱腦損傷;血漿白蛋白;血紅蛋白;預(yù)后
  [中圖分類號(hào)] R651 [文獻(xiàn)標(biāo)識(shí)碼] A [文章編號(hào)] 1674-0742(2018)01(c)-0031-03
  [Abstract] Objective This paper tries to investigate the correlation between serum albumin (Alb) and hemoglobin (HB) level in patients with severe craniocerebral injury (STBI). Methods 64 cases of STBI patients in the hospital from May 2016 to March 2017 were convenient selected and were divided into two groups according to the treatment methods. The control group of 32 cases, patients were given prompt and proper first aid treatment immediately after admission, according to the indications of brain surgery and non-surgical treatment; experimental group of 32 patients, based on the control group added the infusion of human serum albumin and suspended red blood cells to maintain normal Alb and Hb Level. The levels of Alb, Hb and Glasgow Coma Scale(GCS) were recorded during treatment in two groups of STBI patients. The correlation between Alb and Hb levels and the prognosis of STBI patients was compared. Results The survival rate of experimental group was 90.6%, mortality rate was 9.4%, Alb(34.6±2.8)g/L, Hb (99.3±6.4)g/L, significantly better than the control group(P<0.05), Alb<30 g/L, Hb<90 g/L as the death risk factors of STBI. Conclusion The plasma albumin and hemoglobin level are closely correlated with the prognosis of severe craniocerebral injury, and to maintain Alb≥30 g/L and HB≥90 g/L is important to the prognosis of patients.
  [Key words] Severe craniocerebral injury; Plasma albumin; Hemoglobin; Prognosis
  Alb是血漿中最主要的功能性蛋白,是反應(yīng)機(jī)體營養(yǎng)狀態(tài)的重要指標(biāo),而Hb是負(fù)責(zé)運(yùn)載氧的重要蛋白,其功能性與患者機(jī)體損傷存在密切相關(guān)性,故維持STBI患者正常血漿Alb及Hb水平對(duì)改善預(yù)后具有重要意義[1]。該院ICU近年來STBI患者在常規(guī)治療基礎(chǔ)上加用液體療法以長期穩(wěn)定維持STBI患者血漿Alb及Hb水平取得良好治療效果,文章現(xiàn)以2016年5月—2017年4月該院ICU收治的64例STBI患者為例,對(duì)Alb及Hb水平與STBI患者預(yù)后的相關(guān)性進(jìn)行分析和探討,具體報(bào)道如下。
  1 資料與方法
  1.1 一般資料
  以該院ICU收治的64例STBI患者為研究對(duì)象,依治療方式不同將入選病例分為兩組。實(shí)驗(yàn)組(32例):男24例,女8例;年齡(47.9±5.8)歲;入院時(shí)GCS(6.1±0.7)分;APACHEII評(píng)分(24.9±3.2)分。對(duì)照組(32例):男25例,女7例;年齡(47.5±6.3)歲;入院時(shí)GCS(6.2±0.5)分;APACHEII評(píng)分(25.1±2.7)分。兩組一般資料差異無統(tǒng)計(jì)學(xué)意義(P>0.05),具有可比性。

相關(guān)熱詞搜索:白蛋白 顱腦 血紅蛋白 預(yù)后 血漿

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