SPECT/CT,雙時相99mTc-,MIBI斷層顯像在乳腺癌診斷中的應(yīng)用
發(fā)布時間:2018-06-23 來源: 感恩親情 點擊:
摘 要:目的 探討SPECT/CT雙時相 99mTc-MIBI斷層顯像在乳腺癌臨床中的診斷價值。 方法 選取2015 年 1 月~2017 年 5月廣西柳州市中醫(yī)院胸外科收治的女性乳腺疾病患者 98 例進行了術(shù)前兩種檢查方法的診斷,并將診斷結(jié)果記錄,與術(shù)后的病理結(jié)果進行比對。結(jié)果 SPECT/CT雙時相 99mTc-MIBI斷層顯像的敏感性94.80%、特異性90.00%、準確性93.90%,高于鉬靶 X 線檢查的敏感性82.10%、特異性60.00%、準確性77.60%,SPECT/CT雙時相 99mTc-MIBI斷層顯像和鉬靶 X 線檢查對腋窩淋巴結(jié)轉(zhuǎn)移灶的檢出率分別為84.30%和59.40%,兩種檢查方法對乳腺癌的診斷比較均有統(tǒng)計學差異(P<0.05)。 結(jié)論 99mTc- MIBI雙時相斷層顯像對乳腺癌的診斷效能優(yōu)于鉬靶X線檢查,有較高的實用價值。
關(guān)鍵詞:乳腺癌;SPECT/CT;99mTc-MIBI斷層顯像;鉬靶 X 線
中圖分類號:R817.4 文獻標識碼:A DOI:10.3969/j.issn.1006-1959.2018.05.053
文章編號:1006-1959(2018)05-0147-03
Application of SPECT/CT Dual-phase 99mTc-MIBI Tomography in the Diagnosis of Breast Cancer
DONG Yun
。―epartment of Nuclear Medicine,Liuzhou Chinese Medicine Hospital,Liuzhou 545001,Guangxi,China)
Abstract:Objective To evaluate the diagnostic value of SPECT/CT dual-phase 99mTc-MIBI tomography in breast cancer.Methods A total of 98 women with breast diseases admitted in Department of thoracic surgery,Liuzhou Hospital of traditional Chinese medicine in January 2015~2017 May,were selected for the diagnosis of two kinds of examination methods before operation,and the diagnosis results were compared with postoperative pathological results.The results of the two diagnostic methods were compared.Results SPECT/CT 99mTc-MIBI double phase imaging sensitivity of 94.80%,specificity of 90.00%,accuracy of 93.90%,higher than mammography sensitivity 82.10%,specificity 60.00%,accuracy 77.60%,SPECT/CT 99mTc-MIBI double phase imaging and mammography node metastasis detection rates were 84.30% and 59.40% of axillary lymph,two methods in diagnosis of breast cancer were statistically significant(P<0.05).Conclusion 99mTc- MIBI double phase tomography is superior to mammography in diagnosis of breast cancer, and has high practical value.
Key words:Breast cancer;SPECT/CT;99mTc-MIBI tomography;Molybdenum target X-ray
乳腺癌(breast cancer)是婦女最常見的惡性腫瘤之一, 近年來發(fā)病率呈明顯上升趨勢[1],早期診斷對乳腺癌尤其是有腋窩淋巴結(jié)轉(zhuǎn)移者的手術(shù)治療方案及預(yù)后起到至關(guān)重要的作用。一般由體檢或彩超發(fā)現(xiàn)乳房可疑結(jié)節(jié)、腫塊后大多都要進一步做乳腺鉬靶X線檢查。然而,乳腺鉬靶X線檢查對乳腺癌的陽性預(yù)測值較低,對于合并腋窩淋巴結(jié)轉(zhuǎn)移者無法做出特異性判斷[2]。因此,選擇一種改進的非創(chuàng)傷性的技術(shù)檢查乳腺病變,提高其與病理診斷的符合率,具有重要臨床意義。本文對我院胸外科的98例乳腺腫塊患者的術(shù)前乳腺鉬靶X線檢查和99mTc- MIBI雙時相斷層顯像和術(shù)后病理檢查進行了回顧性對比分析, 旨在探討SPECT/CT雙時相 99mTc-MIBI斷層顯像在乳腺癌臨床中的診斷價值。
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