右美托咪定聯(lián)合舒芬太尼用于腹腔鏡子宮全切術(shù)后鎮(zhèn)痛效果分析
發(fā)布時(shí)間:2018-06-24 來(lái)源: 美文摘抄 點(diǎn)擊:
[摘要] 目的 探究腹腔鏡子宮全切術(shù)患者接受右美托咪定與舒芬太尼聯(lián)合對(duì)其術(shù)后鎮(zhèn)痛效果的影響。方法 方便選取該院2015年1月—2017年5月收治腹腔鏡子宮全切術(shù)患者100例作為該次研究對(duì)象,分為2組,其中實(shí)驗(yàn)組在術(shù)后給予其右美托咪定與舒芬太尼聯(lián)合鎮(zhèn)痛,對(duì)照組在術(shù)后僅給予舒芬太尼鎮(zhèn)痛,對(duì)比2組鎮(zhèn)痛效果的差異性。結(jié)果 實(shí)驗(yàn)組疼痛評(píng)分[T1=(2.30±0.51)分,T2=(2.01±0.39)分,T3=(1.71±0.50)分,T4=(1.22±0.47)分,T5=(0.59±0.52)分]均明顯低于對(duì)照組(P<0.05);實(shí)驗(yàn)組鎮(zhèn)痛評(píng)分[T1=(3.41±0.71)分,T2=(2.90±0.69)分,T3=(2.60±0.63)分,T4=(2.51±0.57)分,T5=(2.36±0.52)分]均明顯優(yōu)于對(duì)照組(P<0.05);實(shí)驗(yàn)組腹腔鏡子宮全切術(shù)患者不良反應(yīng)幾率(10.00%)明顯低于對(duì)照組不良反應(yīng)幾率(32.00%)(P<0.05)。結(jié)論 腹腔鏡子宮全切術(shù)患者在術(shù)后接受右美托咪定與舒芬太尼聯(lián)合鎮(zhèn)痛,能夠取得較好的鎮(zhèn)痛效果,且安全性較高。
[關(guān)鍵詞] 右美托咪定;舒芬太尼;腹腔鏡;子宮全切術(shù);鎮(zhèn)痛
[中圖分類(lèi)號(hào)] R4 [文獻(xiàn)標(biāo)識(shí)碼] A [文章編號(hào)] 1674-0742(2018)01(c)-0132-03
[Abstract] Objective This paper tries to investigate the effect of combined dexmedetomidine and sufentanil on postoperative analgesia in patients undergoing laparoscopic hysterectomy. Methods 100 patients undergoing laparoscopic hysterectomy from January 2015 to May 2017 were convenient selected as the study subjects and divided into two groups. The experimental group was given postoperative combination of dexmedetomidine and sufentanil pain, the control group was given only sufentanil analgesia after surgery, the analgesic effects of the two groups were analyzed. Results Pain scores in the experimental group[T1=(2.30±0.51) points, T2=(2.01±0.39)points,T3=(1.71±0.50)points, T4=(1.22±0.47)points, T5=(0.59±0.52)points] were significantly lower than control group(P<0.05); analgesic scores in the experimental group [T1=(3.41±0.71)points, T2=(2.90±0.69) points, T3=(2.60±0.63)points,T4=(2.51±0.57)points, T5=(2.36±0.52)point] were significantly better than the control group(P<0.05); The adverse reaction rate(10.00%) was significantly lower than that in the control group(32.00%)(P<0.05). Conclusion Laparoscopic hysterectomy in patients receiving dexmedetomidine and sufentanil combined analgesia can achieve better analgesic effect, and with higher safety.
[Key words] Dexmedetomidine; Sufentanil; Laparoscopy; Hysterectomy; Analgesia
腹腔鏡子宮全切術(shù)具有較高的應(yīng)用價(jià)值,其對(duì)患者的創(chuàng)傷小,可縮短其術(shù)后恢復(fù)時(shí)間,但是其在術(shù)后仍然存在較為明顯的疼痛,從而對(duì)其術(shù)后恢復(fù)造成一定程度的影響[1-2]。相關(guān)研究表明,手術(shù)后患者的疼痛程度會(huì)對(duì)早期活動(dòng)造成影響,將其術(shù)后恢復(fù)時(shí)間延長(zhǎng),且會(huì)增加并發(fā)癥的發(fā)生幾率,加重患者的心理負(fù)擔(dān)。因此,術(shù)后給予腹腔鏡子宮全切術(shù)患者有效的鎮(zhèn)痛來(lái)促進(jìn)其疼痛程度的減輕,對(duì)其術(shù)后恢復(fù)有著積極的意義。目前,應(yīng)用于術(shù)后疼痛中的藥物之一為舒芬太尼,其是阿片類(lèi)受體激動(dòng)劑,具有較高的選擇性,鎮(zhèn)痛效果較好,但是其鎮(zhèn)靜的效果并不理想,還會(huì)導(dǎo)致患者用藥后出現(xiàn)不良反應(yīng)的情況。右美托咪定是α2腎上腺受體激動(dòng)藥物(高選擇性),其具有鎮(zhèn)痛、鎮(zhèn)靜以及抗焦慮的作用,其協(xié)同阿片類(lèi)藥物進(jìn)行鎮(zhèn)痛,可以將患者的不良反應(yīng)幾率降低。該文主要對(duì)2015年1月—2017年5月50例腹腔鏡子宮全切術(shù)患者接受右美托咪定與舒芬太尼聯(lián)合對(duì)其術(shù)后鎮(zhèn)痛效果的影響作分析,如下。
1 資料與方法
1.1 一般資料
方便選取腹腔鏡子宮全切術(shù)患者100例作為該次研究對(duì)象,根據(jù)其術(shù)后鎮(zhèn)痛措施的不同分為2組,每組50例。
排除標(biāo)準(zhǔn):①精神疾病史者;②嚴(yán)重器質(zhì)性病變者;③阿片類(lèi)藥物過(guò)敏者。
實(shí)驗(yàn)組中,年齡均值為(38.05±11.01)歲,體重均值為(60.23±6.25)kg,手術(shù)時(shí)間均值為(113.56±25.12)min;其中ASAⅠ級(jí)患者19例,ASAⅡ級(jí)患者31例。
相關(guān)熱詞搜索:鎮(zhèn)痛 術(shù)后 子宮 腹腔鏡 用于
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