小劑量多巴胺聯(lián)合托拉塞米治療老年慢性心力衰竭的療效
發(fā)布時間:2018-06-23 來源: 幽默笑話 點擊:
【摘要】 目的 研究小劑量多巴胺聯(lián)合托拉塞米治療老年慢性心力衰竭的臨床效果。方法 130例
老年慢性心力衰竭患者, 采用隨機數(shù)字法分為對照組和觀察組, 各65例。對照組給予呋塞米靜脈注射, 觀察組給予小劑量多巴胺聯(lián)合托拉塞米靜脈注射。對比兩組患者治療效果、不良反應發(fā)生情況及治療前后左心功能變化情況。結(jié)果 觀察組患者的總有效率98.46%(64/65)高于對照組的81.54%(53/65), 差異具有統(tǒng)計學意義(P<0.05)。觀察組不良反應發(fā)生率3.08%(2/65)少于對照組的21.54%(14/65), 差異具有統(tǒng)計學意義(P<0.05)。治療前, 兩組患者的左心室射血分數(shù)(LVEF)、左心室舒張末期內(nèi)徑(LVEDD)水平比較差異無統(tǒng)計學意義(P>0.05);治療后, 兩組患者的LVEF、LVEDD水平均優(yōu)于對照組, 差異具有統(tǒng)計學意義(P<0.05)。結(jié)論 在老年慢性心力衰竭治療采用小劑量多巴胺聯(lián)合托拉塞米具有顯著效果, 能夠有效改善患者心功能指標, 減少不良反應發(fā)生, 具有較高的臨床推廣價值。
【關鍵詞】 多巴胺;托拉塞米;慢性心力衰竭;不良反應;老年
DOI:10.14163/j.cnki.11-5547/r.2018.12.053
【Abstract】 Objective To study the clinical effect of low dose dopamine combined with torasemide in the treatment of elderly patients with chronic heart failure. Methods A total of 130 elderly patients with chronic heart failure were divided by random number table method into control group and observation group, with
65 cases in each group. The control group received intravenous injection of furosemide, and the observation group received low dose dopamine combined with torasemide. Comparison were made on treatment effect, occurrence of adverse reactions and changes of left heart function before and after treatment between the two groups. Results The observation group had higher total effective rate as 98.46% (64/65) than 81.54% (53/65) in the control group, and the difference was statistically significant (P<0.05). The observation group had lower incidence of adverse reactions as 3.08% (2/65) than 21.54% (14/65) in the control group, and the difference was statistically significant (P<0.05). Before treatment, both groups had no statistically significant difference in left ventricular ejection fraction (LVEF) and left ventricular end diastolic diameter (LVEDD) level (P>0.05). After intervention, both groups had better LVEF and LVEDD level than the control group, and the difference was statistically significant (P<0.05). Conclusion Application of low dose dopamine combined with torasemide shows remarkable effect in the treatment of elderly patients with chronic heart failure, and it can effectively improve cardiac function indicator, reduce the incidence of adverse reactions. It contains a high clinical promotion value.
【Key words】 Dopamine; Torasemide; Chronic heart failure; Adverse reactions; Elderly
慢性心力衰竭是臨床內(nèi)科常見疾病, 以老年人為多發(fā)群體, 多數(shù)患者由于心肌梗死、心肌病、血液流動學符合過重而導致心肌受損。病情初期階段, 患者可出現(xiàn)呼吸困難、乏力或體液潴留等臨床表現(xiàn), 隨疾病發(fā)展至晚期, 可出現(xiàn)心源性浮腫, 腎臟等功能則會受到不同程度損傷, 對其生活及健康狀態(tài)造成影響[1-3]。目前, 臨床多采用呋塞米藥物治療, 但長期使用會導致其療效降低, 影響治療效果。本研究選取130例老年慢性心力衰竭患者作為研究對象, 對其中65例采用小劑量多巴胺聯(lián)合托拉塞米治療取得滿意效果, 現(xiàn)報告
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